ISSN 1662-4009 (online)

ey0017.5-4 | Advances in Clinical Practice | ESPEYB17

5.4. Effects of estrogen replacement on bone geometry and microarchitecture in adolescent and young adult oligoamenorrheic athletes: A randomized trial

KE Ackerman , V Singhal , M Slattery , KT Eddy , ML Bouxsein , H Lee , A Klibanski , M Misra

To read the full abstract: J Bone Miner Res. 2020;35(2):248–260.In brief: This randomized open-label trial in oligoamenorrheic athletes evaluated the effects of transdermal estrogen, oral estrogen or no replacement on bone metabolism, geometry, and microarchitecture. Transdermal estrogen treatment resulted in significantly greater increases in volumetric bone mineral d...